![Frontiers | 2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression Frontiers | 2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression](https://www.frontiersin.org/files/Articles/596376/fimmu-12-596376-HTML/image_m/fimmu-12-596376-g009.jpg)
Frontiers | 2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression
![Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma - Tan - 2019 - Cancer Medicine - Wiley Online Library Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma - Tan - 2019 - Cancer Medicine - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/8bced0e3-6008-460f-8fc6-9ffb06271628/cam41971-fig-0001-m.jpg)
Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma - Tan - 2019 - Cancer Medicine - Wiley Online Library
![Frontiers | 2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression Frontiers | 2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression](https://www.frontiersin.org/files/Articles/596376/fimmu-12-596376-HTML/image_m/fimmu-12-596376-g001.jpg)
Frontiers | 2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression
![APExBIO - 2-Methoxyestradiol (2-MeOE2)|Apoptotic, antiproliferative and antiangiogenic agent|CAS# 362-07-2 APExBIO - 2-Methoxyestradiol (2-MeOE2)|Apoptotic, antiproliferative and antiangiogenic agent|CAS# 362-07-2](https://www.apexbt.com/media/diy/images/wb/A4188_2.jpg)
APExBIO - 2-Methoxyestradiol (2-MeOE2)|Apoptotic, antiproliferative and antiangiogenic agent|CAS# 362-07-2
![APExBIO - 2-Methoxyestradiol (2-MeOE2)|Apoptotic, antiproliferative and antiangiogenic agent|CAS# 362-07-2 APExBIO - 2-Methoxyestradiol (2-MeOE2)|Apoptotic, antiproliferative and antiangiogenic agent|CAS# 362-07-2](https://www.apexbt.com/media/diy/images/struct/A4188.png)
APExBIO - 2-Methoxyestradiol (2-MeOE2)|Apoptotic, antiproliferative and antiangiogenic agent|CAS# 362-07-2
![Regulation of mitochondrial dynamics in 2-methoxyestradiol-mediated osteosarcoma cell death | Scientific Reports Regulation of mitochondrial dynamics in 2-methoxyestradiol-mediated osteosarcoma cell death | Scientific Reports](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-020-80816-x/MediaObjects/41598_2020_80816_Fig6_HTML.png)
Regulation of mitochondrial dynamics in 2-methoxyestradiol-mediated osteosarcoma cell death | Scientific Reports
![Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells | Experimental & Molecular Medicine Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells | Experimental & Molecular Medicine](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Femm.2013.104/MediaObjects/12276_2013_Article_BFemm2013104_Fig6_HTML.jpg)
Combination treatment with 2-methoxyestradiol overcomes bortezomib resistance of multiple myeloma cells | Experimental & Molecular Medicine
![NF-κB activation enhances cell death by antimitotic drugs in human prostate cancer cells | Molecular Cancer | Full Text NF-κB activation enhances cell death by antimitotic drugs in human prostate cancer cells | Molecular Cancer | Full Text](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2F1476-4598-9-182/MediaObjects/12943_2009_Article_697_Fig4_HTML.jpg)
NF-κB activation enhances cell death by antimitotic drugs in human prostate cancer cells | Molecular Cancer | Full Text
![2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-κB/HIF-1 signaling pathway inactivation and EMT reversal 2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-κB/HIF-1 signaling pathway inactivation and EMT reversal](https://www.spandidos-publications.com/article_images/or/37/2/OR-37-02-0793-g03.jpg)
2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-κB/HIF-1 signaling pathway inactivation and EMT reversal
![The multifaceted NF-kB: are there still prospects of its inhibition for clinical intervention in pediatric central nervous system tumors? | Cellular and Molecular Life Sciences The multifaceted NF-kB: are there still prospects of its inhibition for clinical intervention in pediatric central nervous system tumors? | Cellular and Molecular Life Sciences](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs00018-021-03906-7/MediaObjects/18_2021_3906_Fig2_HTML.png)
The multifaceted NF-kB: are there still prospects of its inhibition for clinical intervention in pediatric central nervous system tumors? | Cellular and Molecular Life Sciences
![2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-κB/HIF-1 signaling pathway inactivation and EMT reversal 2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-κB/HIF-1 signaling pathway inactivation and EMT reversal](https://www.spandidos-publications.com/article_images/or/37/2/OR-37-02-0793-g02.jpg)
2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-κB/HIF-1 signaling pathway inactivation and EMT reversal
![Inhibition of EZH2 (Enhancer of Zeste Homolog 2) Attenuates Neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-κB (Trimethylation of Histone 3 Lysine 27/Suppressor of Cytokine Signaling 3/Tumor Necrosis Factor Receptor Family 6/Nuclear Factor-κB) in a Rat Model Inhibition of EZH2 (Enhancer of Zeste Homolog 2) Attenuates Neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-κB (Trimethylation of Histone 3 Lysine 27/Suppressor of Cytokine Signaling 3/Tumor Necrosis Factor Receptor Family 6/Nuclear Factor-κB) in a Rat Model](https://www.ahajournals.org/cms/asset/d72d95bf-f067-4dfb-89e4-46e8f2f01731/strokeaha.120.029951.fig06.jpg)
Inhibition of EZH2 (Enhancer of Zeste Homolog 2) Attenuates Neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-κB (Trimethylation of Histone 3 Lysine 27/Suppressor of Cytokine Signaling 3/Tumor Necrosis Factor Receptor Family 6/Nuclear Factor-κB) in a Rat Model
![Anticancer Drug 2-Methoxyestradiol Protects against Renal Ischemia/Reperfusion Injury by Reducing Inflammatory Cytokines Expression Anticancer Drug 2-Methoxyestradiol Protects against Renal Ischemia/Reperfusion Injury by Reducing Inflammatory Cytokines Expression](https://static.hindawi.com/articles/bmri/volume-2014/431524/figures/431524.fig.005a.jpg)
Anticancer Drug 2-Methoxyestradiol Protects against Renal Ischemia/Reperfusion Injury by Reducing Inflammatory Cytokines Expression
![2‐Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF‐1α response after traumatic brain injury in mice - Schaible - 2014 - Journal of Neurochemistry - Wiley Online Library 2‐Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF‐1α response after traumatic brain injury in mice - Schaible - 2014 - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/2204460d-8980-4b46-b112-bee7d5441be6/jnc12708-toc-0001-m.jpg?trick=1707639048425)